en <div style="text-align: justify;"><strong>Aims: </strong>Blood and its pressure is an important issue in trauma and injuries. This study reviewed the pathology of hemodynamic disorders in the light of hemo-mechanics to determine the principles of &quot;Hemomechanics&quot; concerning already proven chemo-physical basis and determine the fluid pressure of the aorta through the mathematical application.<br> <strong>Calculations & Methods:</strong> The article is a mathematical and physical endeavor to resolve the in-depth questions of blood physiology and pathology. Didactic and theoretical methods were used for this research.<br> <strong>Findings:</strong> Changing the latent shear force of blood initiates the wear and tear process in the circulatory system, ultimately damaging the endothelium.<br> <strong>Conclusion:</strong> The four laws of hemomechanics derived here help better understand normal blood physiology, hematology, blood pressure in a broader aspect, and the co-relation of gravitational force with the blood flow in terms of fluidity.<br> &nbsp;</div> Blood,Inflammation,Physiology,Aortic Wall, 131 138 http://ijwph.daneshafarand.org/browse.php?a_code=A-10-1802-1&slc_lang=en&sid=3 S. Samajpaty 1003194753284600378134 1003194753284600378134 Yes Department of General Medicine, International Faculty, Pirogov Russian National Research Medical University (RNRMU), Moscow, Russian Federation