en <p style="text-align: justify;"><strong>Aims:</strong> Eosinopenia is a form of agranulocytosis where the number of eosinophil granulocytes is lower than expected, which is observed in many viral and bacterial infections. This study aimed to investigate eosinopenia in non-respiratory COVID-19 patients.<br> <strong>Materials & Methods: </strong>This experimental study was conducted on COVID-19 patients who had the positive PCR test in an outpatient clinic in Al-Feiha Teaching Hospital in Basrah, Iraq. One hundred four patients were selected from June to November 2020. Full blood counts and estimation of the inflammatory marker C-reactive protein were done. The Chi-square statistical test in SPSS 20 software was used for data analysis.<br> <strong>Findings: </strong>Eosinopenia observed in 47 patients (45.1%); 20 patients (19%) were respiratory COVID-19 and 27 patients (26%) were non-respiratory COVID-19. Total white blood cell count reduced in 17 patients & increased in 30 patients while normal in 57 patients. Logistic regression analysis indicated that eosinopenia is a significant independent predictor of non-respiratory COVID-19 infection (p=0.008; B=0.0001).<br> <strong>Conclusion: </strong>Eosinopenia is a predictor of COVID-19 infection in patients with non-respiratory illnesses.<br> &nbsp;<span dir="RTL"></span></p> Eosinopenia,Non-Respiratory,COVID-19, 185 188 http://ijwph.daneshafarand.org/browse.php?a_code=A-10-1796-1&slc_lang=en&sid=3 T. Kadhim 1003194753284600378225 1003194753284600378225 Yes Department of Internal Medicine, College of Medicine, University of Basrah, Basrah, Iraq H. Abdulilah 1003194753284600378051 1003194753284600378051 No Department of Internal Medicine, College of Medicine, University of Basrah, Basrah, Iraq