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Volume 15, Issue 1 (2023)
3 2023, 15(1): 11-15 |
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Received: 2022/09/19 | Accepted: 2023/01/30 | Published: 2023/02/6
Received: 2022/09/19 | Accepted: 2023/01/30 | Published: 2023/02/6
How to cite this article
Mohi W, Shemran K, Alsaffar Y. Comparison of Visfatin and Leptin Levels in Type 2 Diabetic Patients with and without Atherosclerosis. 3 2023; 15 (1) :11-15
URL: http://ijwph.daneshafarand.org/article-3-85507-en.html
URL: http://ijwph.daneshafarand.org/article-3-85507-en.html
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1- Biochemistry Department, College of Medicine, University of Babylon, Hilla, Iraq
Abstract (2033 Views)
Aims: Medical evidence shows that Visfatin and Leptin are related to multiple metabolic Problems, including obesity, type 2 diabetes, and cardiovascular disease. The present study aimed to assess Visfatin and Leptin levels in type 2 diabetic patients with and without atherosclerosis.
Instruments & Methods: This descriptive study was conducted on 30 diabetic patients, 30 patients with diabetes mellitus and atherosclerosis, and 30 seemingly healthy persons (as a control group) in Babylon Province, Iraq, and their serum Visfatin and Leptin levels were assessed by ELISA procedure. The statistical analysis was done with SPSS 21 software.
Findings: In diabetic patients and patients with diabetes and atherosclerosis, the level of Visfatin was significantly higher than in the control group (p=0.0001). There was a significant increase in Leptin level in diabetic patients compared to the control group (p=0.0001), while Leptin level showed a significant decrease in patients with diabetes and atherosclerosis than in the control group (p=0.0001). Also, the mean body mass index in diabetic patients and patients with diabetes and atherosclerosis was significantly higher than in the control group (p=0.0001).
Conclusion: Visfatin serum levels are significantly higher in atherosclerosis patients compared to healthy people, while low Leptin and high Visfatin expression are seen in patients with diabetes.
Instruments & Methods: This descriptive study was conducted on 30 diabetic patients, 30 patients with diabetes mellitus and atherosclerosis, and 30 seemingly healthy persons (as a control group) in Babylon Province, Iraq, and their serum Visfatin and Leptin levels were assessed by ELISA procedure. The statistical analysis was done with SPSS 21 software.
Findings: In diabetic patients and patients with diabetes and atherosclerosis, the level of Visfatin was significantly higher than in the control group (p=0.0001). There was a significant increase in Leptin level in diabetic patients compared to the control group (p=0.0001), while Leptin level showed a significant decrease in patients with diabetes and atherosclerosis than in the control group (p=0.0001). Also, the mean body mass index in diabetic patients and patients with diabetes and atherosclerosis was significantly higher than in the control group (p=0.0001).
Conclusion: Visfatin serum levels are significantly higher in atherosclerosis patients compared to healthy people, while low Leptin and high Visfatin expression are seen in patients with diabetes.
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