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Volume 14, Issue 4 (2022)
3 2022, 14(4): 409-414 |
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History
Received: 2022/08/1 | Accepted: 2022/11/21 | Published: 2022/11/29
Received: 2022/08/1 | Accepted: 2022/11/21 | Published: 2022/11/29
How to cite this article
AL-Husaini F, Hywar F, Elias N, Falih I. Evaluation of Chemerin in Diabetic Type 2 Patients with Metabolic Syndrome in both Gender. 3 2022; 14 (4) :409-414
URL: http://ijwph.daneshafarand.org/article-3-85500-en.html
URL: http://ijwph.daneshafarand.org/article-3-85500-en.html
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1- Department of Dentistry, Al- Manara College for Medical Sciences, University of Misan, Maysan, Iraq
2- Department of Biochemistry, Al-Zahraa College of Medicine, University of Basrah, Basra, Iraq
3- College of Health and Medical Techniquse, Middle Technical University, Baghdad, Iraq
4- Department of Chemistry, College of Science, University of Misan, Maysan, Iraq
2- Department of Biochemistry, Al-Zahraa College of Medicine, University of Basrah, Basra, Iraq
3- College of Health and Medical Techniquse, Middle Technical University, Baghdad, Iraq
4- Department of Chemistry, College of Science, University of Misan, Maysan, Iraq
Abstract (1716 Views)
Aims: Chemerin abnormal level represents a risk indicator of visceral fat increase. It has a role in the incidence of inflammation, insulin resistance, metabolic syndrome, obesity, and diabetes. This study aimed to evaluate Chemerin level in diabetic type 2 patients with metabolic syndrome in both Genders.
Materials & Methods: This study was carried out on the patients referred to the Al-Yarmouk Teaching Hospital in 2021-2022. 88 participants were selected by random sampling method and were divided into two groups including T2DM patients with metabolic syndrome in the experience group (n=55) compared with healthy subjects in the control group (n=38). Triacylglycerol (TG), High-Density Lipoprotein-Cholesterol (HDL-c), Obesity (BMI), serum Chemerin, Hypertension (SBP), age, Fasting Blood Glucose (FBG), and Glycated Haemoglobin (HbA1C) were measured in the two studied groups. Data were analyzed using T-test through SPSS 21 Software.
Findings: A significant difference was observed between the levels of BMI, SBP, FBG, TG, HDL-c, Chemerin weight, DBP, and HbA1c in the studied groups (p=0.05). The rate of WC and HDL-c was higher in the females than in males in the experience group. While, there was a significant increase in the rates of SBP, FBG, TG, and Chemerin in males than females. A positive correlation coefficient was observed between age, SBP, WC, BMI, FBG, TG, and HbA1c with Chemerin level in the experience group.
Conclusion: An increase in Chemerin level is associated with a high level of triglycerides during the onset of symptoms of metabolic syndrome, age, and gender, which affect the increase of adipokine.
Materials & Methods: This study was carried out on the patients referred to the Al-Yarmouk Teaching Hospital in 2021-2022. 88 participants were selected by random sampling method and were divided into two groups including T2DM patients with metabolic syndrome in the experience group (n=55) compared with healthy subjects in the control group (n=38). Triacylglycerol (TG), High-Density Lipoprotein-Cholesterol (HDL-c), Obesity (BMI), serum Chemerin, Hypertension (SBP), age, Fasting Blood Glucose (FBG), and Glycated Haemoglobin (HbA1C) were measured in the two studied groups. Data were analyzed using T-test through SPSS 21 Software.
Findings: A significant difference was observed between the levels of BMI, SBP, FBG, TG, HDL-c, Chemerin weight, DBP, and HbA1c in the studied groups (p=0.05). The rate of WC and HDL-c was higher in the females than in males in the experience group. While, there was a significant increase in the rates of SBP, FBG, TG, and Chemerin in males than females. A positive correlation coefficient was observed between age, SBP, WC, BMI, FBG, TG, and HbA1c with Chemerin level in the experience group.
Conclusion: An increase in Chemerin level is associated with a high level of triglycerides during the onset of symptoms of metabolic syndrome, age, and gender, which affect the increase of adipokine.