Iranian Journal of War and Public Health

eISSN (English): 2980-969X
eISSN (Persian): 2008-2630
pISSN (Persian): 2008-2622
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Volume 13, Issue 4 (2021)                   3 2021, 13(4): 305-311 | Back to browse issues page

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Dhahir Mansour Al Sultani T, Ayad Fakhri S, Al-Zuhairi W. Comparison of the Antimicrobial Activity of Nigella sativa Aqueous and Oil Extracts. 3 2021; 13 (4) :305-311
URL: http://ijwph.daneshafarand.org/article-3-85439-en.html
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1- Department of Microbiology, Al-Esraa University College, Baghdad, Iraq
2- Department of Pharmacology and Toxicology, Al-Esraa University College, Baghdad, Iraq
3- Pharmacy Department, Al-Esraa University College, Baghdad, Iraq
* Corresponding Author Address: Department of Microbiology, Al-Esraa University College, Baghdad, Iraq (teba.dhaher@esraa.edu.iq)
Abstract   (3013 Views)
Aims: Nigella sativa is recognized as a black seed. It is a grassy plant relating to the Ranunculaceae family. There are various reports regarding this plant's pharmacological and biological action, like antihypertensive effects, antibacterial, anticancer, antioxidants, antifungal, pain alleviating, anti-inflammatory, antidiabetic, and immune-modulatory effects. This study aimed to compare the anti-microbial activity of aqueous and oil extract of Nigella sativa against selected gram-positive and gram-negative bacteria.
Materials & Methods: Nigella sativa aqueous and oil extracts were gathered via a retail food shop (Al-Hilla) 2018. Gram-positive (Staphylococcus aureus; Streptococcus pneumonia; Streptococcus pyogenes) and Gram-negative (Salmonella typhi; Escherichia coli; Pseudomonas aeroginosa) isolates (obtained via clinical specimens) were utilized.
Findings: Both Nigella sativa aqueous and oil extracts showed a maximum inhibition zone against E. coli and minimum inhibition against S. pyogenes.
Conclusion: Nigella sativa acts against gram-positive as well as gram-negative bacterial isolates.
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